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Lynch Syndrome Library

1Risk of Extracolonic Cancers

Risk of Primary Extracolonic Cancers Following Colorectal Cancer in Lynch Syndrome

2. Lynch syndrome resources in Spanish:

TalkingToFamilyAboutLynchSyndrome SPANISH (1)

GeneticTestingCancerPrevention SPANISH (1)

LynchSyndrome SPANISH (1)

3. Lynch syndrome resources in English:




4. Lynch syndrome resources in Tagalog:

Lynch Syndrome Patient Brochure Edited-Tagalog

5. Papers Discussing Lynch syndrome:

6. Educational videos about Lynch syndrome and hereditary cancer

  • When Cancer Runs in the Family: UCSF Mini Medical School Presentation 

Dr. Robert Nussbaum, MD and chief of medical genetics at UCSF, broadly discusses the basics of cancer genetics and why mutations in particular genes cause cancer.

  • Sydney Cancer Genetics Explains Bowel Cancer and Tumor Testing for Lynch Syndrome

Dr. Hilda High from Sydney Cancer Genetics gives an introduction to how Lynch syndrome is identified through tumor screening.

7. Aspirin and its effects on cancer risks in those with Lynch Syndrome: Summary of the CAPP2 study

Long-term effect of aspirin on cancers in carriers with hereditary non polyposis colorectal cancer:  an analysis of the CAPP2 randomized control trial

8. Dr Terdiman on Lynch Syndrome, Aspirin and Cancer Prevention

Lynch Syndrome, Aspirin and Cancer Prevention Final

9. "Aspirin, Ibuprofen, and the Risk of Colorectal Cancer in Lynch Syndrome" 

Aspirin, Ibuprofen and Risk of Colorectal Cancer in Lynch Syndrome

10.  Genetic Counseling Helps Concerned Patients and Families 

Monmouth Medical Center published a wonderful story about two sisters journeys through cancer, genetic testing and a diagnosis of Lynch syndrome.

To read the PDFs of the story click these two links: Monmouth Patient Story and Monmouth Patient Story page 2

11. Lynch Syndrome 101 (Years that is)

This review article discusses the past 100 years of Lynch syndrome including the gene-specific and site-specific cancer penetrance and management options for those with Lynch syndrome.

PDF: Lynch syndrome 101


12. National Comprehensive Cancer Center (NCCN) Guidelines in Oncology for Genetic/Familial High Risk Assesement: Colorectal Cancer

The National Comprehensive Cancer Network® (NCCN®), a not-for-profit alliance of 25 of the world's leading cancer centers devoted to patient care, research, and education, is dedicated to improving the quality, effectiveness, and efficiency of cancer care so that patients can live better lives. Through the leadership and expertise of clinical professionals at NCCN Member Institutions, NCCN develops resources that present valuable information to the numerous stakeholders in the health care delivery system. As the arbiter of high-quality cancer care, NCCN promotes the importance of continuous quality improvement and recognizes the significance of creating clinical practice guidelines appropriate for use by patients, clinicians, and other health care decision-makers.

Many medical centers follow NCCN guidelines for Lynch syndrome genetic testing and screening for Lynch syndrome cancers.

PDF: NCCN Hereditary Colon Cancer Guidelines 1.2014


13. Guidelines on Genetic Evaluation and Management of Lynch Syndrome- A consensus statement by the US Multi-Society Task Force on Colorectal Cancer

The Multi-Society Task Force, in collaboration with invited experts, developed guidelines to assist health care providers with the appropriate provision of genetic testing and management of patients at risk for and affected with Lynch syndrome as follows: Figure 1 provides a colorectal cancer risk assessment tool to screen individuals in the office or endoscopy setting; Figure 2 illustrates a strategy for universal screening for Lynch syndrome by tumor testing of patients diagnosed with colorectal cancer; Figures 3-6 provide algorithms for genetic evaluation of affected and at-risk family members of pedigrees with Lynch syndrome; Table 10 provides guidelines for screening at-risk and affected persons with Lynch syndrome; and Table 12 lists the guidelines for the management of patients with Lynch syndrome. A detailed explanation of Lynch syndrome and the methodology utilized to derive these guidelines, as well as an explanation of, and supporting literature for, these guidelines are provided.

PDF: Guidelines on genetic evaluation and management of Lynch syndrome- A consensus statement by the US Multi-Society Task for on CRC

14. A webcast entailing the facts about Lynch Syndrome