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Lynch Syndrome Podcast Library

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"Ask the Doctor" Series: Podcast 1

"Why do we recommend such frequent colonoscopy in Lynch Syndrome?"

Kintalk specialist speaks with UCSF gastroenterologist and Lynch syndrome expert Jonathan Terdiman, MD (,-md.aspx):

"We frequently hear from our patients with Lynch Syndrome that they have undergone numerous annual “clear” colonoscopies with no polyps identified. They wonder WHY we continue to encourage them to have annual colonoscopy. Can you explain to our listeners why people with Lynch Syndrome must be vigilant and continue their annual colonoscopies to prevent colon cancer?"


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"Ask the Doctor" Series: Podcast 2   

 "Prepping for your colonoscopy"

Kintalk specialist speaks with  UCSF gastroenterologist and Lynch syndrome expert Jonathan Terdiman, MD:

"Dr. Terdiman, can you please tell us why colonoscopy preparation is so important for a successful colonoscopy for patients with Lynch syndrome? And what are the different types of colonoscopy preparation available? Is one better than the other?"


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"Ask the Doctor" Series: Podcast 3         

"Gynecologic Cancers in Lynch Syndrome"

Kintalk specialist speaks with UCSF gynecologic oncologist and Lynch syndrome expert Lee-may Chen, MD (

"Dr. Chen, can you please tell us what are the risks gynecological cancers in women with Lynch Syndrome? Are there obvious signs of these cancers that women should be aware of? Are there a cancer screening test for endometrial and ovarian cancer that can help prevent these cancers? How effective are these tests? Are there any preventative surgeries for these types of cancer? Is there any chemoprevention that might be helpful for women to reduce the risk for endometrial cancer? Are there other things that women with Lynch Syndrome can do to reduce their risk?"


Varma pic"Ask the Doctor" Series: Podcast 4 

"The Role of a Colorectal Surgeon in Lynch Syndrome"

Kintalk specialist speaks with UCSF chief of colorectal surgery, Madhulika Varma, MD.,-md.aspx
"Dr. Varma, when would a person with Lynch syndrome want to meet with a colorectal surgeon? What types of surgical recommendations do you have for a patient with Lynch syndrome who has newly diagnosed with a colon cancer? Can you please describe the difference between a resection of the colon, a subtotal colectomy and a total colectomy? We know that certain procedures might change a person’s lifestyle. Can you please describe to us what those changes are with the different procedures? Lastly, do you have any tips for our listeners for how to find a good colorectal surgeon?"


Van Loon Image"Ask the Doctor" Series: Podcast 5 

"GI Oncology and Lynch syndrome"

Kintalk specialist speaks with UCSF GI onocologist, Katherine Van Loon, MD.
Dr. Van loon answers questions from our Kintalk specialist and Kintalk Community Members.

"There are some features in colon tumors from patients from Lynch Syndrome that differ from colon cancer tumors in the general population.  What are these features, and what do they mean with regards to treatment? In terms of treatment for colon cancer, are there any breakthroughs in the treatment of colon cancer that are promising for the future? As you know, in addition to the high risk for colon cancer in patients with Lynch Syndrome, other gastrointestinal cancers can occur. For example, the risk for small bowel cancer in patient with LS is 3-6% and the risk for pancreas cancer is 3-4%.   What guidance can we give our Lynch Syndrome families to prevent these cancers (or detect them at an early stage)? As a gastrointestinal oncologist, you often meet with patients for second opinions who have been diagnosed with colon cancer at other facilities. To provide them with the best care, what materials do you want to review to their appointment? One Kintalk member asked, “Do colon tumors in people with Lynch syndrome grow quicker than in those people without Lynch syndrome?”"



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"Ask the Doctor" Series: Podcast 6   

"Reproductive Technology and Preimplantation Genetic Diagnosis (PGD)"

Kintalk specialist speaks with UCSF Reproductive Endocrinology and Infertility nurse coordinator Audra Katz, RN.

"What does it mean to “preserve one’s fertility”? What are some of the reasons people choose to preserve their fertility? Ms. Katz, can you please tell who would want to seek your clinics services? What are the different methods used by men and women?  Is there a time frame in which a person must undergo these various procedures? Is there a time frame for when the eggs, embyos and/or sperm must be used? What are the costs of these technologies? Does insurance cover any portion of these services? Can you explain to our listeners, what is PGD and why might person with Lynch Syndrome consider PGD?  How is it done? Are their risks?"


TimBerger.small "Ask the Doctor" Series: Podcast 7 

"Dermatology and Lynch syndrome"

Kintalk specialist speaks with UCSF Dermatologist and Professor of Clinical Dermatology Dr Timothy Berger.
"Tell us about the skin features of Lynch syndrome? What do they look like and on what part of the body are they more likely to occur? How often should a patient come to see their dermatologist if they have been found to have Lynch syndrome? How are these skin tumors treated by the dermatologist? Can people with Lynch syndrome do anything to prevent the development of the skin tumors? If someone has been found to have one of these skin tumors, how likely are they to develop another in their life? Is the average community dermatologist knowledgeable about the skin features of Lynch syndrome? What should patients with Lynch syndrome tell their dermatologist specifically?"


goldmanm_051712crop"Ask the Doctor" Series: Podcast 8

"Surgical Menopause"

Kintalk specialist speaks with UCSF Gynecologist Mindy Goldman, MD who is an Associate Clinical Professor, Department of Obstetrics, Gynecology, and Reproductive Sciences.
Unfortunately, we had some technical issues with the audio. Therefore, we transcribed the podcast. Please read Dr. Goldman's insightful and educational responses about the many things that women need to think about before they undergo risk reducing surgeries that put them into menopause.

Click here: Dr. Goldman Podcast Script 2 (4)


images"Ask the Expert" Series: Podcast 9 

"Nutrition for Cancer Prevention and Hereditary Cancer"

Kintalk specialist speaks with UCSF registered dietitian, Greta Macaire about diet and exercise’s impact on a person’s risk for cancer. To learn more about Greta please go to her UCSF profile:

"We work with many families who have Lynch syndrome, an inherited colon and uterine cancer predisposition, and Hereditary Breast and Ovarian Cancer Syndrome due to mutations in their BRCA1 and BRCA2 genes.  Are there an diet and physical activity factors that affect the risk for: Breast, Colon, Ovarian and Uterine Cancer? Are there any foods and physical activities that you would recommend a person should avoid as they would increase a person’s risk for cancer? Unfortunately, many of our patients are currently undergoing treatment for cancer. Are there any special foods or physical activities that you recommend while they are going through their cancer treatment? One of our Kintalk members asked, So many of us have heard a glass of red wine is good for our heart health but that too much wine or alcohol can increase a person’s chance for getting cancer.  Can you please clarify how much alcohol is considered beneficial vs harmful? Do you have any recommendations for how a personal can help maintain these healthy eating habits and physical activity?"


Here are some wonderful resources for nutrition and cancer prevention:

1. Article: American Cancer Society Guidelines on Diet and Physical Activity for Cancer Prevention:

2. Video: Eating for Life: Nutrition Strategies to optimize health after cancer treatment by Greta Macaire