RAD51C gene

The RAD51C gene is a gene involved in the Fanconi anemia (FA)–BRCA pathway, which is critical for DNA repair by homologous recombination and interact in vivo with BRCA1 and/or BRCA2. Mutations in this gene is estimated to increase a person’s lifetime risk for breast cancer by 4 fold. Current studies are looking to see if there is a link to an increased risk of ovarian cancer as well.