BRIP1 gene

The BRIP1 gene is involved in the Fanconi anemia (FA)–BRCA pathway, which works with other important genes and is critical for DNA repair. Mutations in these genes are estimated to increase a person’s lifetime risk for ovarian cancer. Current studies are looking to see if there is a link to an increased risk of ovarian cancer as well.

Resources

National Cancer Institute: Genetics of Breast and Ovarian Cancerhttp://www.cancer.gov/cancertopics/pdq/genetics/breast-and-ovarian/HealthProfessional/page3